Malaysian Applied Biology Journal

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48_02_11

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Malays. Appl. Biol. (2019) 48(2): 77–81

 

DEVELOPMENT OF NANOEMULSION INCORPORATED WITH

Hibiscus sabdariffa FOR COSMECEUTICAL APPLICATION


NUR ROYHAILA MOHAMAD1, SITI SALWA ABD GANI1,2*, ROSWANIRA ABDUL WAHAB3

and USWATUN HASANAH ZAIDAN4


1Halal Products Research Institute (HPRI), Putra Infoport, Universiti Putra Malaysia, UPM,

43400 Serdang, Selangor, Malaysia

2Department of Agriculture Technology, Faculty of Agriculture, Universiti Putra Malaysia, UPM,

43400 Serdang, Selangor, Malaysia

3Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia,

81310 UTM Johor Bahru, Malaysia

4Department of Biochemistry, Faculty of Biotechnology & Biomolecular Sciences,

Universiti Putra Malaysia, UPM, 43400 Serdang, Selangor, Malaysia

*E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


Accepted 8 May 2019, Published online 31 May 2019


ABSTRACT

Hibiscus sabdariffa (HS) has been reported to possess a crucial content of bioactive compounds, such as phenolic acids and flavonoids, therefore, HS was recognized as a source of antioxidants. Due to that, the development of nanoemulsion incorporated with HS appears promising for cosmeceutical application. This study is focused on the formulation of oil-inwater (O/W) nanoemulsions of HS to enhance the bioaccessibility of its active compounds. The influences of hydrophiliclipophilic balance (HLB) value of surfactant and grapeseed oil (GSO) to olive oil (OO) ratio on the droplet size, zeta potential, PDI and stability of the nanoemulsions were investigated. The results showed that the smallest particle size was obtained at 145.9 nm with PDI = 0.388 and zeta-potential = -41.1 mV in the systems prepared using HLB value of 12 and 2:1 ratio of GSO to OO. Then the selected nanoemulsion which based on the lowest particle size (NE-F6, GSO:OO = 2:1, and HLB = 12) showed good stability over time and temperature without no phase separation, creaming or cracking was spotted. The pH value of the NE-F6 was obtained at 5.2.


Key words: Hibiscus sabdariffa, nanoemulsion, oil ratio, HLB value

 

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